The game which ended 2-3 in favor of Tottenham saw strikes from Tottenham’s Harry Kane, Son and Lucas moura.
Tottenham took a 2 nil lead into the break with a strike from Son in the 36th minute and another from Lucas in the 43rd minute.
Harry Kane made it 3 four minutes into the second half and although the hammers did hammer in one in the 73rd minute through Antonio and a 96th minute goal from Ogbonna, the win was to be that of the men from white hart lane.
The win raises Tottenham up from 14th on the table to 6th in the meantime.
Mourinho was appointed over the week following the axing of former spurs boss Pochettino after an abysmal start to the season by last Seasons Champions league finalist.